Rapid formation and resolution of cataracts following orthopedic surgery for a patient with Charcot-Marie-Tooth disease.

not find reduced levels of macular pigments in our lightsensitive subjects. Instead, we found that subjects with migraine had significantly higher levels of macular pigments compared with a control group. Although patients with blepharospasm had lower levels of macular pigments, this difference was not statistically significant. It is not possible to tell from our experiments why migraineurs with chronic light sensitivity accumulate higher levels of macular pigment or whether this accumulation is clinically significant. It is possible that the macula accumulates these compounds in an effort to mitigate light sensitivity. The mechanisms that underlie carotenoid absorption, protein binding, transport, and storage are highly complex. There are numerous points in these processes where carotenoid metabolism could be affected in some light-sensitive individuals. In conclusion, a deficiency of macular pigments does not appear to be involved in the pathogenesis of photophobia in patients with light sensitivity. Further research will need to be completed to elucidate the pathophysiology of photophobia.